Aging Aggravates Nitrate-Mediated ROS/RNS Changes

Table 1

Baseline Characteristics of the Study Population (mean ± SD).

	MI adult (𝑛=34)	MI elderly (𝑛=45)	𝑃
Age, y	50.1±6.6	73.7±4.8	<0.001
Sex, M/F	28/4	24/19	<0.01
HBP/total	23/32	35/43	NS
Dyslipidemia/total	21/32	34/43	NS
Diabetes/total	20/32	29/43	NS
Smoker/total	24/32	29/43	NS
Past drug treatment (𝑛/total)
Statins	17/32	30/43	NS
Calcium channel blocker	9/32	18/43	NS
ACEI	15/32	31/43	<0.05
ß-Adrenoceptor blocker	8/32	26/43	<0.01
Diuretic	5/32	20/43	<0.01
Drug treatment during the study (𝑛/total)
Statins	32/32	43/43	NS
Calcium channel blocker	19/32	32/43	NS
ACEI	17/32	27/43	NS
ß-Adrenoceptor blocker	21/32	27/43	NS
nitrates	32/32	43/43	NS
Mean dosage of nitrates (μg/min)	50	50	NS

HBP indicates high blood pressure; ACEI: angiotensin-converting enzyme inhibitor; y: year; M: male; F: female.