Clinical Study
Aging Aggravates Nitrate-Mediated ROS/RNS Changes
Table 1
Baseline Characteristics of the Study Population (mean ± SD).
| | MI adult () | MI elderly () | |
| Age, y | | | <0.001 | Sex, M/F | 28/4 | 24/19 | <0.01 | HBP/total | 23/32 | 35/43 | NS | Dyslipidemia/total | 21/32 | 34/43 | NS | Diabetes/total | 20/32 | 29/43 | NS | Smoker/total | 24/32 | 29/43 | NS | Past drug treatment (/total) | | | | Statins | 17/32 | 30/43 | NS | Calcium channel blocker | 9/32 | 18/43 | NS | ACEI | 15/32 | 31/43 | <0.05 | ß-Adrenoceptor blocker | 8/32 | 26/43 | <0.01 | Diuretic | 5/32 | 20/43 | <0.01 | Drug treatment during the study (/total) | | | | Statins | 32/32 | 43/43 | NS | Calcium channel blocker | 19/32 | 32/43 | NS | ACEI | 17/32 | 27/43 | NS | ß-Adrenoceptor blocker | 21/32 | 27/43 | NS | nitrates | 32/32 | 43/43 | NS | Mean dosage of nitrates (μg/min) | 50 | 50 | NS |
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HBP indicates high blood pressure; ACEI: angiotensin-converting enzyme inhibitor; y: year; M: male; F: female.
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