[Retracted] Antiaging Properties of a Grape-Derived Antioxidant Are Regulated by Mitochondrial Balance of Fusion and Fission Leading to Mitophagy Triggered by a Signaling Network of Sirt1-Sirt3-Foxo3-PINK1-PARKIN

Table 1

Effect of resveratrol and longevinex on myocardial function.

	Control	Resveratrol	Longevinex
Coronary flow (mL/min)
Baseline	24±2.1	25±3.0	24±2.4
60 min rep.	22±2.3	24±2.5	23±3.1
120 min rep.	23±2.0	24±2.8	25±1.9
Aortic flow (mL/min)
Baseline	51±2.3	53±4.0	52±3.8
60 min rep.	25±3.2	35±3.7	38±2.7
120 min rep.	8.5±2.7	24±3.2	26±3.5
LVDP (mm Hg)
Baseline	116±6	117±7	119±9
60 min rep.	80±5	98±5	101±6
120 min rep.	54±7	84±7	86±5
LVmaxdp/dt (mm Hg/sec)
Baseline	3056±48	1845±45	1028±56
60 min rep.	1689±65	2356±33	1754±39
120 min rep.	1206±38	1877±62	2012±32
Infarct size (infarct area/area of risk)
Baseline	3±2	2.8±1.2	2.1±0.8
120 min rep.	36±4	19±3	17±2
Apoptosis (%)
Baseline	1±1	1±0.8	1±0.7
120 min rep.	22±3	9±2	8±2