[Retracted] Antiaging Properties of a Grape-Derived Antioxidant Are Regulated by Mitochondrial Balance of Fusion and Fission Leading to Mitophagy Triggered by a Signaling Network of Sirt1-Sirt3-Foxo3-PINK1-PARKIN
Figure 6
Transmission electron microscopy images showing the ultrastructure findings in control and resveratrol treated hearts. Cardiomyocytes from control show normal ultrastructure and resveratrol treated hearts show mitophagy. Autophagosomes in resveratrol treated samples TEM images show early autophagic vacuoles containing still identifiable organelles (a–c) and late autophagosomes containing lamellar and vesicular structures (d–f). Autophagosomes preferentially contain mitochondria (m) enclosed by distinctive double membrane (arrows).
