Polyphenols: Multipotent Therapeutic Agents in Neurodegenerative Diseases

Table 2

Modulation of cytokines and inflammatory targets by polyphenols.

Polyphenol	Target	References
EGCG	IL-1β	[115]
	IL-6	[116]
	MCP-1	[115]
	CXCL 10,	[116]
	CCL22, CCL 17	[117]
	TGF β	[117]
Resveratrol	MCP-1	[118]
Catechin	MCP-1 (α and β)	[119]
Caffeic acid	CCR1, CCR2	[119]
Quercetin	IL-1β, IL-6	[120]
	COX-2	[120]
	COX-20, TRAF1	[121]
Apple polyphenols	IL-1β, IL-6, IL-17, IL-22; CXCL-9, CXCL-10, CXCL-11,	[122, 123]