Review Article
SOD1 and DJ-1 Converge at Nrf2 Pathway: A Clue for Antioxidant Therapeutic Potential in Neurodegeneration
Table 2
Synthetic activators of Nrf2/ARE signalling pathway.
| Molecule | Model | Reference |
| Triterpenoids | ā | ā | CDDO-EA | MPTP-treated mice (model of PD) | Kaidery et al., 2013 [117] | CDDO-TFEA | Cellular models and SOD1-G93A transgenic mice (model of ALS) | Neymotin et al., 2011 [118] | CPN-9 | Cellular models and SOD1H46R transgenic mice (model of ALS) | Kanno et al., 2012 [119] | Bromocriptine | PC12 cells | Lim et al., 2008 [120] | Azathioprine | Cellular and transgenic mice (models of skin and liver carcinoma) | Kalra et al., 2011 [121] |
|
|