SOD1 and DJ-1 Converge at Nrf2 Pathway: A Clue for Antioxidant Therapeutic Potential in Neurodegeneration

Table 2

Synthetic activators of Nrf2/ARE signalling pathway.

Molecule	Model	Reference
Triterpenoids
CDDO-EA	MPTP-treated mice (model of PD)	Kaidery et al., 2013 [117]
CDDO-TFEA	Cellular models and SOD1-G93A transgenic mice (model of ALS)	Neymotin et al., 2011 [118]
CPN-9	Cellular models and SOD1^H46Rtransgenic mice (model of ALS)	Kanno et al., 2012 [119]
Bromocriptine	PC12 cells	Lim et al., 2008 [120]
Azathioprine	Cellular and transgenic mice (models of skin and liver carcinoma)	Kalra et al., 2011 [121]