Astragalus Polysaccharide Suppresses Skeletal Muscle Myostatin Expression in Diabetes: Involvement of ROS-ERK and NF-κB Pathways
Figure 6
Effects of APS on NF-κB activation in palmitate-stimulated C2C12 cells. C2C12 cells were incubated for 24 h in DMEM containing 5% BSA in either the presence (FFA-treated cells) or absence (control cells) of 0.5 mmol/L FFAs. Cells treated with APS were incubated with additional APS at the final concentration of 200 μg/mL. The expression of nuclear NF-κB and cytoplasmic IκBa was determined by western blot. Data are expressed as means ± SD of 6 different experiments. ### versus vehicle, **, *** versus palmitate. NF-κB: nuclear factor-kappa B.
