Astragalus Polysaccharide Suppresses Skeletal Muscle Myostatin Expression in Diabetes: Involvement of ROS-ERK and NF-κB Pathways

Figure 2

Effect of APS on MDA production and myostatin expression in skeletal muscle. At the end of 8-week APS administration, skeletal muscle MDA level (a), myostatin protein (b), and mRNA expression (c) were assessed, respectively. Results are expressed as means ± SD for 6 animals in each group. ^###𝑃<0.001 versus C57BL/6J, **𝑃<0.01, ***𝑃<0.001 versus KKAy. MDA: malondialdehyde; MSTN: myostatin.

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(b)

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