Astragalus Polysaccharide Suppresses Skeletal Muscle Myostatin Expression in Diabetes: Involvement of ROS-ERK and NF-κB Pathways

Figure 1

Effect of APS on blood glucose level (a), insulin resistance index HOMA score (b), plasma FFAs level (c), and body weight (d). Changes in blood glucose and body weight were evaluated before and after APS treatment for 8 weeks. Insulin resistance HOMA score and plasma FFAs were examined at the end of 8-week APS administration. Results are expressed as means ± SD for 8 animals in each group. ^###𝑃<0.001 versus C57BL/6J at the same age, *𝑃<0.05, ***𝑃<0.01 versus KKAy at the same age. HOMA: homeostasis model assessment; FFA: free fatty acids.

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