Acute Oral Toxicological Profile of Croton membranaceus Mull. Arg. Aqueous Stem Extract, a Herbal Treatment for Benign Prostate Hyperplasia, in Male Sprague–Dawley Rats

Table 3

Effect of single-dose administration of CMASE (1000, 2500, and 5000 mg/kg) on organ weights of male S-D rats on the 14th day.

Organ	Control	Low dose	Median dose	High dose	values
Kidney (g)	1.20 ± 0.08	1.24 ± 0.06	1.04 ± 0.08	1.16 ± 0.07	0.97
Liver (g)	6.73 ± 0.19	6.87 ± 0.40	6.67 ± 0.21	7.00 ± 0.52	0.91
Heart (g)	0.62 ± 0.02	0.64 ± 0.04	0.56 ± 0.03	0.60 ± 0.05	0.52

Data are presented as mean ± SEM. n = 5. There were no significant differences between treatment groups and control group using one-way ANOVA ().