Research Article

Acute and Subchronic Toxicity Assessment of Conventional Soxhlet Cymbopogon citratus Leaves Extracts in Sprague–Dawley Rats

Table 2

Effect of six weeks of oral administration of CSE C. citratus ethanolic extract on lipid profile at termination of the experiment.

ParameterTreatment group
ControlConventional Soxhlet ethanolic C. citratus extract
200 mg/kg600 mg/kg1200 mg/kg

Total cholesterol1.51 ± 0.330.52 ± 0.030.84 ± 0.350.55 ± 0.06
Triglyceride0.51 ± 0.021.81 ± 0.062.07 ± 0.261.76 ± 0.03
HDL cholesterol0.98 ± 0.030.46 ± 0.040.58 ± 0.050.35 ± 0.03
LDL cholesterol0.45 ± 0.071.12 ± 0.040.92 ± 0.131.10 ± 0.03
Coronary risk1.54 ± 0.321.12 ± 0.071.46 ± 0.281.56 ± 0.06

Values are mean ± SEM of n = 6, , compared to control.