Acute and Subchronic Toxicity Assessment of Conventional Soxhlet Cymbopogon citratus Leaves Extracts in Sprague–Dawley Rats

Figure 6

Representative micrographs of the kidney tissue in Sprague–Dawley rats after six weeks of CSE C. citratus ethanolic extract administration (x100). The micrographs show mainly glomeruli (G) and renal tubules (T) lined by a single layer of epithelial cells with regular nuclei. No tubular atrophy, interstitial fibrosis, or inflammatory infiltrates are noted. (a) Kidney tissue of control rats treated with sterilized distilled water. (b) Kidney tissue of rats treated with 200 mg/kg bw.t CSE C. citratus ethanolic extract. (c) Kidney tissue of rats treated with 600 mg/kg bw.t CSE C. citratus ethanolic extract. (d) Kidney tissue of rats treated with 1200 mg/kg bw.t CSE C. citratus ethanolic extract.

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