Anticancer Activity of Rhizophora mucronata Leaves Extract on Sprague–Dawley Rats: In Vivo Model

Figure 20

Histopathology analysis of mammary tissue: (a) control, (b) 20 mg/kg DMBA induced, (c) methanolic extract of R. mucronata 250 mg/kg treated, and (d) 20 mg/kg fluorouracil standard control. (a) Normal duct lobule units with fatty tissues. (b) High mitotic activity with the necrosis and reactive lymphatic follicular hyperplasia. (c) Hyperchromasia. (d) Terminal duct lobule with some neoplastic cells.

(a)

(b)

(c)

(d)