Protective Effects of Sanyar Prebiotic on Immunity and Tissue Changes of Common Carp (Cyprinus carpio) Exposed to CuSO₄ Stress

Table 4

The common lesions of the fish exposed to the concentration of copper after 96 h.

A: gill
Hyperplasia	Epithelial cells necrosis of gill	Expansion of secondary lamella	Hyperemia	Hemorrhage	Edema	Concentrations (mg/l)
+++	++	++	++	++	++	P0
+++	++	++	++	++	++	P1
++	++	++	++	++	++	P2
++	++	++	++	++	++	P3
B: kidney
Inflammatory cells infiltration	Hyperemia	Hemorrhage	Necrosis of tubule		Concentrations (mg/l)
++	+	+	+		P0
++	+	−	+		P1
+	−	−	−		P2
+	−	−	−		P3
C: liver
Inflammatory cells infiltration	Hyperemia	Hemorrhage	Necrosis		Concentrations (mg/l)
++	+	−	−		P0
++	+	−	−		P1
+	−	−	−		P2
+	−	−	−		P3

(−): No lesions; (+): lesions <20%; (++): lesions> 20–60%; (+++): lesions> 60%.