Research Article

Quercetin Zinc and Iron Metal Complexes Protect against Sodium Arsenite Intoxication in the Hepato-Renal System of Wistar Rats via the Oxidative Stress Pathway

Table 1

Effect of quercetin and its complexes on the body weight, relative kidney and liver weight of sodium arsenite-induced alterations in rats.

Groups% increase in body weightRelative kidney weight (mg/100 g)Relative liver weight (mg/100 g)

Normal control54.630.007 ± 0.0010.037 ± 0.001
NaAr-induced rats35.74#0.007 ± 0.0010.037 ± 0.001
NaAr + quercetin44.07#0.007 ± 0.0010.035 ± 0.002
NaAr + qquercetin-Zn45.46#0.007 ± 0.0010.039 ± 0.004
NaAr + quercetin-Fe47.540.007 ± 0.00150.034 ± 0.001

Normal control = normal rats; NaAr-induced rats = sodium arsenate-intoxicated rat; Na-Ar + quercetin = sodiumarsenate-intoxicated rat + 30 mg/kg quercetin treatment; Na-Ar + quercetin-Zn = sodium arsenate-intoxicatedrat + quercetin-Zn complex treatment; Na-Ar + quercetin-Fe. significant difference with sodium arsenite intoxicated rats, #significant difference with control rats.