Prenatal Developmental Toxicity and Histopathological Changes of the Placenta Induced by Syzygium guineense Leaf Extract in Rats

Table 3

Fetal growth indices of rat fetuses following the administration of 70% ethanol leaf extract of Syzygium guineense.

Variables	Group
	250 mg/kg n = 10	500 mg/kg n = 10	1000 mg/kg n = 10	Control n = 10	Ad libitum control n = 10
CRL/fetus (cm)	5.3 ± 0.2	5.2 ± 0.4	5.0 ± 0.4	5.5 ± 0.2	5.7 ± 0.4
Fetal weight (g)	5.8 ± 0.9	5.1 ± 0.5	4.9 ± 0.5	5.5 ± 0.6	5.1 ± 0.8
Placental weight (g)	0.7 ± 0.2	0.6 ± 0.1	0.6 ± 0.1	0.7 ± 0.1	0.6 ± 0.05

The results are expressed as mean ± SDM, significant difference with control and ad libitum control groups ( value <0.05), One-Way ANOVA; CRL: Crown-rump length.