The Protective Effects of Nigella sativa and Its Constituents on Induced Neurotoxicity

Table 2

The protective effect of Nigella sativa and its constituents on neurodegeneration and Alzheimer disease (AD).

Drug	Dose	Result	References
N. sativa	400 mg/kg	No histopathological changes observed in the frontal cortex and brain stem	[12]
N. sativa and TQ	400 mg/kg and 50 mg/kg	No histopathological changes observed in hippocampus	[13]
TQ	50 mg/kg	Protective effects in frontal cortex	[14]
TQ	(0.1, 1, 10, and 100 nm)	Significant improvement in cell survival	[16]
TQ	5 mg/kg/day	Increased GSH contents, catalase, and SOD activities and also decreased the elevated of MDA	[17]