Review Article
Nanotechnology Role Development for COVID-19 Pandemic Management
Table 1
Summary of the role of nanomaterials for COVID-19.
| Key role for COVID-19 | Nanomaterial | Purpose |
| Diagnostics | Magnetic nanoparticle | (i) Conjugated with a probe is used to detect complementary target sequence of SARS-CoVs | Metal nanoparticle | (ii) Modified (nucleic acid or protein bound) and integrated into COVID-19 sensors, mostly for colorimetric detection | Carbon-based nanoparticle | (iii) Integrated into diagnostic platform for COVID-19 detection | Quantum dot | (iv) Incorporated into sensor, acting as fluorescent label for COVID-19 detection |
| Prevention | Metal nanoparticle | (i) Induce structural changes in viral S protein, resulting in viral neutralization | Carbon-based nanoparticle | (ii) Inactivate virus and inhibit its entry into host cells | Quantum dot | (iii) Prevent viral RNA genome amplification |
| Treatment | Metal nanoparticle Carbon-based | (i) Antiviral activity is achieved by altering the structural properties of virus S protein | Nanoparticle | (ii) Inhibit the virus's ability to enter host cells by destroying it. | Quantum dot | (iii) Inhibit binding of S protein receptor of coronavirus to host cells | Exosome | (iv) Target, bind, and suppress cellular uptake of coronavirus |
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