Review Article

Nanotechnology Role Development for COVID-19 Pandemic Management

Table 1

Summary of the role of nanomaterials for COVID-19.

Key role for COVID-19NanomaterialPurpose

DiagnosticsMagnetic nanoparticle(i) Conjugated with a probe is used to detect complementary target sequence of SARS-CoVs
Metal nanoparticle(ii) Modified (nucleic acid or protein bound) and integrated into COVID-19 sensors, mostly for colorimetric detection
Carbon-based nanoparticle(iii) Integrated into diagnostic platform for COVID-19 detection
Quantum dot(iv) Incorporated into sensor, acting as fluorescent label for COVID-19 detection

PreventionMetal nanoparticle(i) Induce structural changes in viral S protein, resulting in viral neutralization
Carbon-based nanoparticle(ii) Inactivate virus and inhibit its entry into host cells
Quantum dot(iii) Prevent viral RNA genome amplification

TreatmentMetal nanoparticle
Carbon-based
(i) Antiviral activity is achieved by altering the structural properties of virus S protein
Nanoparticle(ii) Inhibit the virus's ability to enter host cells by destroying it.
Quantum dot(iii) Inhibit binding of S protein receptor of coronavirus to host cells
Exosome(iv) Target, bind, and suppress cellular uptake of coronavirus