Research Article

Inhibition of Neutrophil Collagenase/MMP-8 and Gelatinase B/MMP-9 and Protection against Endotoxin Shock

Table 3

Peptide treatment strategy for the animal experiment in Figure 4(a).

GroupPeptide administration strategy

G1 ( = 16)LPS (100 μL*, iv),
G2 ( = 12)LPS (100 μL, iv), 5 minutes later, P2 (100 μL***, iv)
G3 ( = 12)LPS (100 μL, iv), 5 minutes later, P2 (100 μL, iv),
2 hours later, P2 (100 μL, iv)

LPS is dissolved in sterile 0.9% saline at a concentration of 2 μg/µL. Peptide P2 is dissolved in sterile 0.9% saline at a concentration of 2.0 mg/mL.