Association of Monocyte-to-HDL Cholesterol Ratio with Endothelial Dysfunction in Patients with Type 2 Diabetes
Table 1
Clinical characteristics of patients included.
All ()
Nonendothelial dysfunction ()
Endothelial dysfunction ()
value
Men (%)
146 (60.1)
26.0 (52.0)
120 (62.0)
0.35
Age (years)
65.7 (59.6-72.4)
63 (54.6-67)
66.6 (60-73)
0.004
Smoking (%)
60 (24.7)
9 (18.0)
51 (26)
0.21
Drinking (%)
61 (25.1)
7 (14.0)
54 (28)
0.10
BMI (kg/m2)
24.2 (22.4-26.3)
24.2 (22.1-26.2)
24.4 (22.5-26.4)
0.48
Disease course (%)
10.0 (3.00-20.0)
10.0 (2.00-16.0)
10.0 (4.00-20.0)
0.30
SBP (mmHg)
0.001
DBP (mmHg)
0.012
Hypertension (%)
147 (60.5)
25 (50.0)
122 (63)
0.09
FBG (mmol/l)
7.70 (5.90-10.2)
7.85 (5.93-10.2)
7.60 (5.85-10.2)
0.89
HbA1c (%)
9.6 (7.9-11.2)
9.2 (7.9-11.2)
9.7 (7.9-11.3)
0.46
Fasting C-peptide(mmol/l)
0.35 (0.19-0.60)
0.34 (0.16-0.60)
0.35 (0.19-0.60)
0.57
HOMA-IR
26.2 (14.4-48.1)
19.6 (10.6-51.6)
27.3 (14.9-47.1)
0.44
TC (mmol/l)
4.59 (3.72-5.56)
4.75 (3.80-5.57)
4.51 (3.71-5.56)
0.82
TG (mmol/l)
1.42 (0.99-2.05)
1.37 (0.99-2.06)
1.43 (1.00-2.06)
0.52
HDL-C (mmol/l)
1.07 (0.94-1.26)
1.05 (0.94-1.37)
1.07 (0.95-1.26)
0.78
LDL-C (mmol/l)
2.95 (2.3-3.62)
2.89 (2.42-3.61)
2.96 (2.26-3.63)
0.89
WBC (109/l)
6 (4.9-7.1)
5.5 (4.9-6.4)
6.1 (4.9-7.2)
0.12
Monocyte (109/l)
0.43 (0.35-0.54)
0.37 (0.31-0.50)
0.45 (0.37-0.55)
0.002
MHR
0.009
FMD (%)
<0.001
Data are presented as median (IQR) for continuous variables and number (proportion%) for category variables. Differences in medians were examined using the Mann–Whitney test between two groups. Differences in proportions were tested using the chi-square test. BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; FPG: fasting plasma glucose; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; WBC: white blood cell; MHR: monocyte-to-high-density lipoprotein cholesterol ratio.
