Plasma AGE and Oxidation Products, Renal Function, and Preeclampsia in Pregnant Women with Type 1 Diabetes: A Prospective Observational Study

Table 5

Plasma concentrations of soluble receptor for advanced glycation end products (sRAGE) and ratios of sRAGE versus advanced glycation end products (AGE), during gestation and prior to the onset of preeclampsia.

		DM+PE+ ()	value	DM+PE- ()	value^#	DM- ()
sRAGE^†	V1		0.08		0.76
	V2		0.018		0.93
	V3		0.64		0.58
sRAGE/CML^‡	V1		0.13		0.42
	V2		0.037		0.23
	V3		0.84		0.84
sRAGE/CEL^‡	V1		0.37		0.92
	V2		0.019		0.68
	V3		0.93		0.33
sRAGE/MGH1^‡	V1		0.72		0.73
	V2		0.87		0.96
	V3		0.47		0.38
sRAGE/3DGH^‡	V1		0.67		0.07
	V2		0.15		0.07
	V3		0.65		0.68
sRAGE/GH1^‡	V1		0.97		0.40
	V2		0.47		0.99
	V3		0.80		0.76

Data are presented as . Units: ^†pg/mL; ^‡g/moles. Independent sample tests were used as appropriate. Boldface indicates values < 0.05 (statistically significant). value, DM+PE- vs. DM+PE+. ^# value, DM+PE- vs. DM-.