Plasma AGE and Oxidation Products, Renal Function, and Preeclampsia in Pregnant Women with Type 1 Diabetes: A Prospective Observational Study

Table 1

Baseline maternal characteristics of women with type 1 diabetes with and without preeclampsia and of normotensive non-diabetic women.

	DM+PE+ ()	value	DM+PE– ()	value^#	DM– ()
Age of woman (years)		0.31		0.25
Duration of diabetes (years)		0.32		—	—
BMI (kg/m^2)		0.028		0.50
HbA1c (%)		0.046		<0.0001
HbA1c (mmol/mol)		0.046		<0.0001
MAP (mm Hg)		0.21		0.14
Total cholesterol (mmol/L)		0.53		0.18
HDL cholesterol (mmol/L)		0.029		0.71
LDL cholesterol (mmol/L)		0.08		0.18
Triacylglycerols (mmol/L)		0.27		0.09
Microalbumin:creatinine ratio	0.7 (0.5, 1.2)	0.62	0.7 (0.4, 1.0)	0.40	0.8 (0.6, 1.0)
eGFR (mL min^-1 1.73 m^-2)		0.015		0.92

Data are presented as , or median (interquartile range). Measurements refer to visit 1, at study entry. The independent sample tests and Mann–Whitney tests were used as appropriate. eGFR was defined using Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. Boldface indicates values < 0.05 (statistically significant). value, DM+PE- vs. DM+PE+. ^# value, DM+PE- vs. DM-.