Increased Insulin Secretion and Glucose Effectiveness in Obese Patients with Type 2 Diabetes following Bariatric Surgery

<div>Correlation between the incremental increase in total insulin secretion index (<span class="nowrap"><svg height="11.9087pt" id="M134" style="vertical-align:-3.2728pt" version="1.1" viewbox="-0.0498162 -8.6359 28.693 11.9087" width="28.693pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M600 0V24L339 665L311 657L43 24V0H600ZM497 50H107L303 539L497 50Z"></path></g><g transform="matrix(.013,0,0,-0.013,8.144,0)"><path d="M488 658H270V630C328 626 335 619 335 579C217 574 44 509 44 330C44 147 221 88 335 86C335 38 328 32 265 28V0H488V28C425 32 418 38 418 86C534 88 710 153 710 337C710 517 538 575 418 579C418 619 425 626 488 630V658ZM335 118C249 124 136 180 136 337C136 490 251 543 335 547V118ZM418 547C502 543 618 491 618 333S503 124 418 118V547Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,17.946,3.132)"><path d="M298 36L289 62C276 55 253 45 228 45C202 45 169 60 169 141V397H276C289 405 292 426 282 437H169V574L155 576L90 509V437H45L17 408L21 397H90V107C90 28 125 -12 188 -12C198 -12 213 -8 230 1L298 36Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,20.667,3.132)"><path d="M257 449C165 449 37 374 37 209C37 98 119 -12 256 -12C355 -12 473 65 473 226C473 349 381 449 257 449ZM244 416C333 416 380 320 380 204C380 67 329 21 267 21C184 21 130 115 130 241C130 354 184 416 244 416Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,25.207,3.132)"><path d="M298 36L289 62C276 55 253 45 228 45C202 45 169 60 169 141V397H276C289 405 292 426 282 437H169V574L155 576L90 509V437H45L17 408L21 397H90V107C90 28 125 -12 188 -12C198 -12 213 -8 230 1L298 36Z"></path></g></svg>)</span> and incremental increase in area under GLP-1 (<i>Δ</i>AUC(GLP-1), a) and GIP (<i>Δ</i>AUC(GIP), b) concentrations. RYGB: Roux-en Y gastric bypass; SG: sleeve gastrectomy.</div>

Journal of Diabetes Research

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Figure 5

Figure 5: Increased Insulin Secretion and Glucose Effectiveness in Obese Patients with Type 2 Diabetes following Bariatric Surgery 