The Effects of Antioxidants and Pulsed Magnetic Fields on Slow and Fast Skeletal Muscle Atrophy Induced by Streptozotocin: A Preclinical Study

Figure 3

Pulsed magnetic field (PMF) treatment system and application protocol. (a) A suitably sized Plexiglas enclosure was positioned in the homogeneity region of the 95% consistent magnetic field between Helmholtz coils (). A signal generator was used to generate a magnetic field amplitude of 1.5 mT between these coils. (b) The circuit’s current () was observed using an oscilloscope via a resistor (0.1 ohm) that was linked in series between the signal generator’s output and the coil. The time-varying magnetic field was made up of a quasitriangular waveform with a rise time of 0.5 ms and a fall time of 9.5 ms (dashed line). (c) A schematic protocol for the pulsed magnetic field was applied to animals once daily for two hours immediately following the antioxidant injection. The peak amplitude of the magnetic field was 1.5 mT, the frequency was 10 Hz, the pulse width was 0.5 ms, and the number of pulses in each train was 2400. The train duration was 4 minutes, and the interval between trains was 1 minute. The number of trains in each cycle was 3, and the total number of cycles was 8.

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