Colquhounia Root Tablet Promotes Autophagy and Inhibits Apoptosis in Diabetic Nephropathy by Suppressing CD36 Expression In Vivo and In Vitro

Figure 4

CRT promotes the proliferation and inhibits the apoptosis of Hg-induced HK-2 cells. (a) Cell viability of different drug concentrations using CCK-8 assay. (b) Cell viability of different experimental groups using CCK-8 assay. (c) Apoptotic HK-2 cells were determined using flow cytometry under conditional treatment. (d) Representative transmission electron microscopy images of autophagosomes in HK-2 cells, with yellow arrows indicate autophagosomes. Scale  μm. Results represent for three independent experiments. , , , compared with the Con group; ^#, ^##, ^###, compared with the Hg group.

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