Research Article

The Composite Autonomic Symptom Score 31 Questionnaire: A Sensitive Test to Detect Risk for Autonomic Neuropathy

Table 2

COMPASS 31 score for groups.

Group score, points
Longstanding diabetesEarly diabetesControl valueAll groups

Orthostatic0.0 (0.0-14.0)0.0 (0.0-0.0)0.0 (0.0-0.0)0.230.0 (0.0-12.0)
Vasomotor0.0 (0.0-0.0)0.0 (0.0-0.0)0.0 (0.0-0.0)0.760.0 (0.0-0.0)
Secretomotor4.3 (0.0-6.4)†0.0 (0.0-0.0)2.1 (0.0-4.3)0.031.1 (0.0-4.8)
Gastrointestinal5.4 (2.7-8.9)1.8 (0.0-6.3)2.7 (0.0-7.1)0.063.6 (0.9-7.1)
Bladder1.1 (0.0-2.8)1.1 (0.0-2.2)1.1 (0.0-2.2)0.811.1 (0.0-2.2)
Pupillomotor1.0 (0.3-2.0)1.0 (0.0-2.0)1.0 (0.0-1.7)0.491.0 (0.0-1.7)
Total weighted14.9 (10.8-28.7)††7.3 (1.6-15.2)8.6 (4.1-21.6)0.0411.9 (4.5-21.6)

Data are medians with interquartile range, values comparing all three groups using the Kruskal-Wallis test. †Significant in pairwise comparison to early diabetes. ††Significant in pairwise comparison to both other groups. For pairwise comparison, the Mann–Whitney test was used.