Research Article
Fibroblast Growth Factor 21 in Gestational Diabetes Mellitus and Type 2 Diabetes Mellitus
Table 1
General and biochemical data of type 2 diabetic patients, gestational diabetic patients, and the respective control groups.
| | Parameter | Studied groups | value (diabetes type 2 vs. control 1) | value (gestational diabetes vs. control 2) | | Diabetes type 2 () | Control 1 () | Gestational diabetes () | Control 2 () |
| | Age (years) | | | | | — | — | | Gender | Male: 30 (50.8%)
Female: 29 (49.2%) | Male: 31 (56.4%)
Female: 24 (43.6%) | Female: 80 (100%) | Female: 32 (100%) | — | — | | Glucose (mmol/L) | | | | | | — | | Insulin (μIU/mL) | 13.2 (9.27-19.7) | 9.80 (7.36-12.6) | 12.9 (8.62-18.47) | 11.0 (7.64-13.38) | | — | | HOMA-IR (mmol/L × μU/mL) | 3.73 (2.42-7.36) | 1.78 (1.26-2.40) | 2.63 (1.68-3.59) | 2.0 (1.37-2.83) | | — | | HbA1c (%, mmoL/moL) | 8.10 (7.0-9.1)
65.0 (53.0-76.0) | — | 5.45 (4.90-6.00)
36.1 (30.1-42.1) | — | — | — | | TC (mmol/L) | | | | | | — | | HDL-C (mmol/L) | | | | | | — | | TG (mmol/L) | 2.80 (1.86-3.73) | 1.28 (0.94-1.57) | 2.03 (1.60-2.59) | 2.32 (1.82-2.57) | | — | | FGF21 (pg/mL) | 355.68 (178.3-697.1) | 83.0 (54.5-124.0) | 84.1 (38.6-153.7) | 54.6 (20.4-134.6) | | — |
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HbA1c: glycated hemoglobin; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; TG: triglycerides; FGF21: fibroblast growth factor 21.
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