Factors Affecting Intensive Aflibercept Treatment Response in Diabetic Macular Edema: A Real-World Study

Figure 1

Mean changes in central retinal thickness and best-corrected visual acuity in the whole cohort. Mean changes in central retinal thickness (CRT) and best-corrected visual acuity (BCVA) with 95% confidence interval error bars during the loading phase (months 0-4) and maintenance phase (PRN regimen, months 5-12). For month five, the result of the five monthly loading aflibercept injections is indicated by the vertical black dotted line. (significant difference compared to the baseline value in repeated measures ANOVA, ).