Research Article
Pleiotropic Effects of a KCNQ1 Variant on Lipid Profiles and Type 2 Diabetes: A Family-Based Study in China
Table 3
Mediation analysis of the association between the KCNQ1 rs2237895 and T2DM risk mediated by lipid parameters.
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OR: odds ratio; CI: confidence interval; PM: proportion mediated; T2DM: type 2 diabetes mellitus; TC: total cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; Apo-A: apolipoprotein A; Apo-B: apolipoprotein B. Notes: all models were adjusted for age, sex, smoking and drinking status, hypertension, coronary heart disease, and body mass index. Lipid parameters with significant indirect effects are shown in bold. |