Journal of Diabetes Research

Research Article

Association of Serum Adiponectin with Intima Media Thickness of Dorsalis Pedis Artery and Macroangiopathy in Type 2 Diabetes

Table 3

Clinical characteristics among the different subgroups.
Clinical measurementHigh-adiponectin subgroup ()Moderate-adiponectin subgroup ()Low-adiponectin subgroup () value
Age (y)0.323
Male, (%)29 (40.85)32 (45.07)39 (54.93)0.226
Cigarette smoking, (%)23 (32.39)25 (35.21)32 (45.07)0.262
Alcohol drinking, (%)44 (61.97)47 (66.20)49 (69.01)0.673
BMI (kg/m2)<0.001
Diabetes duration (y)0.5 (0, 6)#7 (2, 11.5)6 (3, 10)<0.001
SBP (mmHg)125 (120, 131)135 (130, 155)155 (132, 160)<0.001
DBP (mmHg)84.58 ± 9.19<0.001
FPG (mmol/L)6.10 (5.39, 9.11)9.08 (7.25, 12.62)8.81 (7.92, 10.56)<0.001
PPG (mmol/L)9.86 (6.30, 14.25)14.60 (11.58, 18.40)14.25 (12.30, 17.20)<0.001
HbA1C (%)<0.001
TC (mmol/L)0.024
TG (mmol/L)1.10 (0.74, 1.68)1.65 (1.25, 2.17)1.48 (1.02, 1.98)0.036
HDL-C (mmol/L)<0.001
LDL-C (mmol/L)#0.003
UA (mmol/L)<0.001
Fg (g/L)0.133
Fins (μU/mL)#<0.001
HOMA2-IR1.10 (0.60, 1.60)1.80 (1.50, 3.10)2.70 (1.70, 3.50)<0.001
hs-CRP (mg/L)1.01 (0.79, 1.92)3.04 (0.94, 3.62)4.72 (4.20, 6.95)<0.001
D-IMT (cm)#<0.001
Adiponectin (mg/L)#<0.001
Macroangiopathy, (%)7 (9.86%)30 (42.25%)46 (64.79%)<0.001
Significantly different from the high-adiponectin level subgroup. #Significantly different from the moderate-adiponectin level subgroup. BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; FPG: fasting plasma glucose; PPG: postprandial 2 hours blood glucose; HbA1C: glycosylated hemoglobin; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; UA: uric acid; Fg: fibrinogen; Fins: fasting insulin; HOMA2-IR: homeostasis model assessment 2 of insulin resistance; hs-CRP: high-sensitivity C-reactive protein; D-IMT: intima media thickness of the dorsalis pedis artery. Measurement data are presented as or median (with interquartile ranges).