Research Article

Scutellarin Prevents Angiogenesis in Diabetic Retinopathy by Downregulating VEGF/ERK/FAK/Src Pathway Signaling

Figure 8

Schema: the antitubulogenic mechanism of SCU on diabetic retinopathy. SCU attenuates the retinal tubulogenesis induced by hyperglycemia and hypoxia, by decreasing the expression of VEGF and in turn suppressing the phosphorylation of FAK, Src, and ERK.