Scutellarin Prevents Angiogenesis in Diabetic Retinopathy by Downregulating VEGF/ERK/FAK/Src Pathway Signaling

<div>SCU downregulated the activation of p-ERK, p-FAK, p-Src, and VEGF but did not affect the expression of PEDF in the retina of DR rats. (a) Western blot analysis was used to determine the protein expression of VEGF, PEDF, FAK, p-FAK, Src, p-Src, ERK, and p-ERK in the retina of diabetic rats. GAPDH was used as loading control. Bar graphs in (b)–(f) present quantitative difference in expression of independent experiments. 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Journal of Diabetes Research

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Figure 7

Figure 7: Scutellarin Prevents Angiogenesis in Diabetic Retinopathy by Downregulating VEGF/ERK/FAK/Src Pathway Signaling 