Journal of Diabetes Research / 2018 / Article / Tab 2

Research Article

Higher Concentrations of BCAAs and 3-HIB Are Associated with Insulin Resistance in the Transition from Gestational Diabetes to Type 2 Diabetes

Table 2

NMR metabolites at follow-up 6 years after GDM pregnancy.

%NGTIGTT2DM (BMI adjusted)
MeanSDMeanSDMeanSDIGT versus NGTT2D versus NGTT2D versus IGTIGT versus NGTT2D versus NGTT2D versus IGT

Phenylalanine100.045.4121.843.8117.149.10.02
Tyrosine100.025.1109.626.9111.626.70.03
Glucose100.020.7112.118.1159.579.6<0.001<0.001<0.001<0.001
Mannose100.025.9113.426.2144.359.5<0.001<0.001<0.001<0.001
Glycerol100.043.1127.548.6140.771.10.006<0.0010.007<0.001
Glycine100.027.088.119.189.625.60.020.050.04
Citrate100.031.0111.523.9117.325.70.0020.002
Pyruvate100.080.6141.378.2119.473.70.0080.01
Acetoacetate100.0105.8115.7103.9253.1348.8<0.0010.001<0.0010.001
3-HIB100.054.7128.252.7131.575.50.020.0060.0050.002
Valine100.019.2108.215.1109.521.60.040.010.05
Isoleucine100.022.1109.019.0115.728.5<0.0010.001
Leucine100.018.2111.213.6113.422.70.002<0.0010.010.001

Metabolites significantly different between groups are shown. Data is expressed as % of NGT. Statistics are performed using ANOVA () and ANCOVA (BMI-adjusted ). for NGT, for IGT, and for T2DM.

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