Diabetic Retinopathy in the Spontaneously Diabetic Torii Rat: Pathogenetic Mechanisms and Preventive Efficacy of Inhibiting the Urokinase-Type Plasminogen Activator Receptor System

Figure 4

Retinal vascular phenotype. (a, b) Representive images of flat-mounted retinas from SD control rats (a) and untreated SDT rats (b) immunolabeled with a rat monoclonal antibody directed to CD31. The superficial vascular plexus is shown. No altered pattern of retinal vasculature in the superficial vascular plexus was observed in untreated SDT rats. CD31 immunohistochemistry was performed on 3 retinas from 3 different rats for each experimental condition. Scale bar: 1 mm.

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