Transcriptome Profiles Using Next-Generation Sequencing Reveal Liver Changes in the Early Stage of Diabetes in Tree Shrew (Tupaia belangeri chinensis)

Figure 1

Biochemical parameters in healthy control tree shrews and STZ-induced diabetic tree shrews over 8 weeks. (a) Body weight; (b) plasma concentration of fasting blood glucose; (c) serum concentration of HbA1c; (d) serum concentration of triglycerides (TAG); (e) serum concentration of cholesterol (CHOL); (f) serum concentration of high-density lipoprotein cholesterol (HDL); (g) serum concentration of low-density lipoprotein cholesterol (LDL); (h) serum concentration of alanine aminotransferase (ALT); (i) serum concentration of aspartate aminotransferase (AST). in control group; in diabetic group. Significance between two groups. Control group versus 8 weeks of diabetic group: , , and ; control group versus 4 weeks of diabetic group: , , and .

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