Change in Long-Spacing Collagen in Descemet's Membrane of Diabetic Goto-Kakizaki Rats and Its Suppression by Antidiabetic Agents
Figure 5
Immunoelectron-microscopic
detection of type VIII collagen in Descemet’s membrane by the colloidal gold labeling
method. (a) In the cornea of a 15-week-old Wistar rat, the colloidal gold label
is distributed diffusely in the membrane. (b) In the diabetic cornea of a
15-week-old GK rat, the gold marker is mainly observed in the internodal region
of the long-spacing collagen. Scale bar, 100 nm.