Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents

<div>Vasospastic venous angiopathy. Edematous fluid, released from the lysed muscle cells, containing newly forming granulation tissue and cellular debris widely separates surviving medial and adventitial muscle and compresses and disrupts the intima. Hematoxylin &amp; eosin ×100 (adapted from the World Journal Cardiovascular Diseases 2013.3 published online).</div>

International Journal of Vascular Medicine

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Figure 32

Figure 32: Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents 

Figure 32 | Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents 