Effect of Transcriptional Regulator ID3 on Pulmonary Arterial Hypertension and Hereditary Hemorrhagic Telangiectasia

Figure 3

Diagram of how transcriptional regulator ID3 affects various pathways in HHT and PAH. Pathways included are ALK1/SMAD1-5, ALK/SMAD2-3, NOTCH, EPHRINB2–VEGFR2, and ALK1/ACTR2 via BMP or TGF-β signaling.