Occipital Artery Function during the Development of 2-Kidney, 1-Clip Hypertension in Rats
Table 1
Body and tissue weight parameters in SHAM and 2K-1C rats on day 9.
Parameter
SHAM
2K-1C
Mean arterial blood pressure, mmHg
96 ± 1
120 ± 4*
Peak systolic arterial blood pressure, mmHg
105 ± 3
134 ± 5*
Heart rate, beats/min
340 ± 12
396 ± 9*
Plasma renin concentration, g/mL
68 ± 2
106 ± 13*
Body weight, g
426 ± 13
413 ± 14
Nonclipped kidney weight, g
1.2 ± 0.04
1.4 ± 0.06*
Nonclipped kidney weight/body weight, mg/g
2.9 ± 0.08
3.3 ± 0.09*
Clipped kidney weight, g
1.2 ± 0.05
1.0 ± 0.03*
Clipped kidney weight/body weight, mg/g
2.8 ± 0.08
2.4 ± 0.09*
Heart weight, g
1.35 ± 0.04
1.48 ± 0.06*
Heart weight/body weight, mg/g
3.2 ± 0.04
3.6 ± 0.08*
The data are presented as mean ± SEM. SHAM: sham-operated rats; 2K-1C: 2-kidney, 1-clip rats. There were 8 rats in each group. P < 0.05 in 2K-1C versus SHAM.