Research Article

Occipital Artery Function during the Development of 2-Kidney, 1-Clip Hypertension in Rats

Table 1

Body and tissue weight parameters in SHAM and 2K-1C rats on day 9.

ParameterSHAM2K-1C

Mean arterial blood pressure, mmHg96 ± 1120 ± 4*
Peak systolic arterial blood pressure, mmHg105 ± 3134 ± 5*
Heart rate, beats/min340 ± 12396 ± 9*
Plasma renin concentration, g/mL68 ± 2106 ± 13*
Body weight, g426 ± 13413 ± 14
Nonclipped kidney weight, g1.2 ± 0.041.4 ± 0.06*
Nonclipped kidney weight/body weight, mg/g2.9 ± 0.083.3 ± 0.09*
Clipped kidney weight, g1.2 ± 0.051.0 ± 0.03*
Clipped kidney weight/body weight, mg/g2.8 ± 0.082.4 ± 0.09*
Heart weight, g1.35 ± 0.041.48 ± 0.06*
Heart weight/body weight, mg/g3.2 ± 0.043.6 ± 0.08*

The data are presented as mean ± SEM. SHAM: sham-operated rats; 2K-1C: 2-kidney, 1-clip rats. There were 8 rats in each group. P < 0.05 in 2K-1C versus SHAM.