The Effect of Lymph Nodes’ Histologic Response on Survival Outcomes in Moroccan Patients with Rectal Cancer

Table 2

Univariate analysis for OS and RFS among patients with rectal cancer according to different characteristics.

Characteristics	Overall survival			Relapse-free survival
	OS (%)	95% CI		RFS (%)	95% CI
Age
65	70.64	65.74–75.55	<0.001	NA	—	0.427
65–75	72.46	64.43–80.49		NA	—
75–85	69.19	57.80–80.58		NA	—
85	36.50	0.00–15.32		NA	—
Sex
Men	69.75	63.49–76.01	0.600	59.46	50.99–67.92	0.684
Women	69.53	64.10–74.96		60.18	52.54–67.81
Histologic type
Adenocarcinoma	70.71	66.50–74.91	0.607	NA	—
Mucinous/signet ring cell	57.00	24.74–89.25		NA	—
Therapeutic effect
Absence	47.31	33.53–61.09	0.041	36.21	18.53–53.89	0.098
Presence	71.69	67.52–75.85		61.74	55.82–67.88
Fibrosis TE on LNs
Absence	58.84	42.45–75.23	0.038	49.57	27.70–71.44	0.300
Presence	70.27	66.23–74.31		60.06	54.25–65.87
Colloid TE on LNs
Absence	61.69	53.27–70.10	0.001	54.66	44.23–65.10	0.279
Presence	74.15	69.79–78.51		62.74	55.98–69.50
Necrosis TE on LNs
Absence	63.62	55.74–71.50	0.009	58.42	48.67–68.17	0.549
Presence	73.26	69.07–77.44		60.30	53.33–67.26
Regression types grouped on 5						0.427
0TE	47.31	33.53–61.09	0.051
2+	71.80	64.43–79.16		NA	—
3+	73.11	68.84–77.38		NA	—
C+	60.00	24.79–95.20		NA	—
F+	62.81	53.19–72.43		NA	—
Regression types grouped on 4						0.331
0TE	47.31	33.53–61.09	0.028	NA	—
C+	60.00	24.79–95.20		NA	—
F+	62.81	53.19–72.43		NA	—
ME+	72.98	68.86–77.09		NA	—

TE: therapeutic effect; LNs: lymph nodes; 0TE: absence of therapeutic effect; 2+: combination of two therapeutic effect types; 3+: combination of three therapeutic types; F+: fibrosis effect; C+: colloid effect; NA: not applicable.