Research Article
Predictive Factors of Positive Circumferential and Longitudinal Margins in Early T3 Colorectal Cancer Resection
Table 1
Distribution of the studied cases according to different clinicopathological parameters (n = 50).
| | | No. (%) |
| | Sex | | | Male | 31 (62%) | | Female | 19 (38%) | | Age (years) | | | Median (min.–max.) | 63 (49–72) | | Mean ± SD | 63.8 ± 4.1 | | Site | | | Colon | 41 (82%) | | Rectum | 9 (18%) | | Size | | | Median (min.–max.) | 4 (3–6) | | Mean ± SD | 4.3 ± 1 | | Gross appearance | | | Ulcer | 15 (30%) | | Infiltrating | 12 (24%) | | Fungating | 23 (46%) | | Histopathological type | | | Adenocarcinoma | 26 (52%) | | Mucinous | 15 (30%) | | Signet ring | 9 (18%) | | Depth | | | Pericolorectal tissue/serosa | 20 (40%) | | Muscularis propria | 30 (60%) | | Advancing tumor front | | | Invasive pattern | 37 (74%) | | Broad pushing margin (cohesive pattern) | 13 (26%) | | Desmoplasia | 20 (40%) | | Tumor budding | 18 (36%) | | Lymph nodes involvement | 16 (32%) | | Inflammation | 27 (54%) | | Necrosis | 19 (38%) | | Perineural invasion | 5 (10%) | | Vascular invasion | 10 (20%) | | Tumor grade | | | G1 | 15 (30%) | | GII | 17 (34%) | | GIII | 18 (36%) | | Mitotic index | | | Median (min.–max.) | 8 (1–11) | | Mean ± SD | 6.4 ± 3.1 | | Apoptotic index | | | Median (min.–max.) | 9 (2–15) | | Mean ± SD | 7.7 ± 3.7 | | MVD | | | Median (min.–max.) | 8 (2–18) | | Mean ± SD | 7.7 ± 3.4 | | Sinusoidal vascular pattern | | | Negative | 39 (78%) | | Positive | 11 (22%) | | Positive longitudinal resection margin | 6 (12%) | | Positive circumferential resection margin | 17 (34%) |
|
|
