Molecular and Genetic Basis of Inherited Nephrotic Syndrome

Figure 1

(a) Low-power view of glomerular filtration barrier in situ. The glomerular filter consists of three components: porous endothelium, glomerular basement membrane, and podocyte foot processes with the interposed slit membrane. Figure is transmission electron microscopy from a rat. Magnification: B, x~48,000. (b) Schematic drawing of the molecular equipment of the podocyte foot processes, similar to the area marked in Figure 1(a). See text for further explanations, (modified from [23]).