Research Article
Novel Antimicrobial Agents: Fluorinated 2-(3-(Benzofuran-2-yl) pyrazol-1-yl)thiazoles
Table 3
Minimum inhibitory concentration (μg/mL) against the pathological strains based on twofold serial dilution technique.
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Chem. compds | Gram-positive bacteria | Gram-negative bacteria | Yeast | Staphylococcus aureus ATCC29213 | B. subtilis ATCC6633 | B. megaterium ATCC9885 | Sarcina lutea | Klebsiella pneumoniae ATCC13883 | Pseudomonas aeruginosa ATCC27953 | E. coli ATCC25922 | Saccharomyces cerevisiae | Candida albicans NRRL Y-477 |
| 5 | 200 | — | 200 | 100 | 100 | 100 | 100 | 100 | 200 | 8a | 19 | 16 | 200 | 100 | — | 200 | 100 | 200 | 200 | 8b | 100 | 200 | — | 50 | 200 | 200 | 100 | 200 | — | 8c | 50 | 50 | 100 | 50 | 25 | 50 | 25 | 200 | 100 | 8d | 50 | — | — | 100 | — | 200 | 100 | 200 | 200 | 13a | 200 | 200 | 200 | 100 | 200 | 200 | 100 | 200 | — | 13b | 100 | 200 | 50 | 100 | 100 | 200 | 100 | 200 | — | 14 | 200 | 200 | 200 | 100 | 100 |
100 | 50 | 100 | 200 | 15 | 200 | — | 200 | 10 0 | 100 | 200 | 50 | 200 | 200 | 16 | 200 | — | 20 | 100 | 100 | 200 | 50 | 200 | — | Ciprofloxacin | 25 | 25 | 25 | 25 | 25 | 25 | 25 | N.A. | N.A. | Ketoconazole | N.A. | N.A. | N.A. | N.A. | N.A. | N.A. | N.A. | 25 | 25 |
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