Emergency Medicine International / 2019 / Article / Tab 4

Research Article

Cognitive Impairment among Cardiac Arrest Survivors in the ICU: A Retrospective Study

Table 4

Comparison of serum biomarkers between patients with and without cognitive impairment (n = 53).

First cognitive assessmentLast cognitive assessment
MMSE ≥ 24 (n = 12)MMSE < 24 (n = 41)MMSE ≥ 24 (n = 35)MMSE < 24 (n = 18)

NSE 0 h, ng/mL (n = 48)22.03 (15.30–31.52)18.59 (15.08–22.80)0.20619.09 (13.84–23.05)20.05 (16.85–26.66)0.301
NSE 24 h, ng/mL (n = 45)19.94 (15.67–24.10)19.20 (15.16–22.27)0.65317.86 (14.95–21.80)21.40 (18.02–26.19)0.030
NSE 48 h, ng/mL (n = 37)11.27 (7.66–17.48)12.40 (8.17–17.33)0.60411.58 (7.98–17.44)15.20 (7.86–17.29)0.425
NSE 72 h, ng/mL (n = 23)9.70 (8.01–19.86)11.29 (10.51–12.90)0.80410.78 (8.30–13.85)13.64 (11.09–13.65)0.315
S100B 0 h, ng/mL (n = 51)0.27 (0.18–1.62)0.29 (0.15–0.95)0.4640.23 (0.17–0.67)0.37 (0.15–1.75)0.411
S100B 24 h, ng/mL (n = 51)0.08 (0.06–0.09)0.09 (0.06–0.11)0.4840.07 (0.05–0.10)0.09 (0.07–0.13)0.022
S100B 48 h, ng/mL (n = 46)0.07 (0.06–0.10)0.10 (0.06–0.12)0.3950.07 (0.06–0.11)0.11 (0.08–0.15)0.009
S100B 72 h, ng/mL (n = 25)0.07 (0.04–0.08)0.06 (0.04–0.09)0.9120.06 (0.04–0.08)0.08 (0.06–0.11)0.111

MMSE, Mini-Mental State Examination; NSE, neuron-specific enolase; S100B, S100 calcium-binding protein B.

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