Research Article
HIV Virologic Failure among Patients with Persistent Low-Level Viremia in Nairobi, Kenya: It Is Time to Review the >1000 Virologic Failure Threshold
Table 2
Baseline characteristics of patients with PLLV (categorical variables) between 2015 and 2021 at Kenyatta National Hospital.
| Variables | Frequency | % | |
| Age group | | | 1 to 9 | 42 | 6.0 | 10 to 19 | 43 | 6.1 | 20 to 24 | 22 | 3.1 | 25 to 30 | 31 | 4.4 | 31 to 40 | 127 | 18.0 | 41 to 50 | 240 | 34.0 | 51 and above | 200 | 28.4 | Age description | | | Child | 42 | 6.0 | Adolescent | 43 | 6.1 | Youth | 22 | 3.1 | Older adults | 598 | 84.8 | Gender | | | Male | 317 | 45.0 | Female | 388 | 55.0 | Education | | | None | 4 | 0.6 | Preschool | 16 | 2.3 | Primary | 133 | 18.9 | Secondary | 156 | 22.1 | Postsecondary | 88 | 12.5 | Not documented | 308 | 43.6 | Marital status | | | Child | 63 | 8.9 | Single | 163 | 23.1 | Married | 358 | 50.8 | Separated/divorced | 40 | 5.7 | Widowed | 49 | 7.0 | Not documented | 32 | 4.5 | Age at HIV diagnosis | | | 1 to 9 | 74 | 10.4 | 10 to 19 | 18 | 2.5 | 20 to 29 | 57 | 8.1 | 30 to 39 | 133 | 18.9 | 40 to 49 | 71 | 10.1 | 50 and above | 28 | 4.0 | Not documented | 324 | 46.0 | Years positive | | | 0 to 5 | 58 | 8.2 | 6 to 10 | 140 | 19.9 | 11 and above | 194 | 27.5 | Not documented | 313 | 44.4 | Baseline WHO stage | | | Stage 1 | 244 | 34.6 | Stage 2 | 95 | 13.5 | Stage 3 | 155 | 22.0 | Stage 4 | 59 | 8.4 | Not documented | 152 | 21.5 | Baseline viral load | | | Nondetectable | 263 | 37.3 | 20 to 999 | 281 | 39.9 | 1000 and above | 161 | 22.8 | TB history | | | Yes | 106 | 15.0 | No | 599 | 85.0 | OI history | | | Yes | 555 | 78.7 | No | 150 | 21.3 | PCP | | | Yes | 4 | 0.6 | No | 701 | 99.4 | Cryptococcal disease | Yes | 4 | 0.6 | No | 701 | 99.4 | Oral candidiasis | | | Yes | 32 | 4.5 | No | 673 | 95.5 | Kaposi’s sarcoma | | Yes | 3 | 0.4 | No | 702 | 99.6 | Other cancers | | | Yes | 15 | 2.1 | No | 690 | 97.9 | Hypertension | | | Yes | 92 | 13.0 | No | 613 | 87.0 | Diabetes | | | Yes | 23 | 3.3 | No | 682 | 96.7 | Renal disease | | | Yes | 22 | 3.1 | No | 683 | 96.9 | IPT status | | | Completed | 401 | 56.9 | Deferred | 137 | 19.4 | Start | 21 | 3.0 | Continuing | 35 | 5.0 | Declined | 10 | 1.4 | Defaulted | 4 | 0.6 | Not documented | 97 | 13.7 | Start VL at PLLV | | 20 to 199 | 532 | 75.5 | 200 to 499 | 113 | 16.0 | 599 to 999 | 60 | 8.5 | Start regimen | | | 2NRTI+1PI/r | 133 | 18.9 | 2NRTI+1NNRTI | 545 | 77.3 | 2NRTI+1INSTI | 27 | 3.8 | Switched regimen at PLLV | | Yes | 329 | 46.7 | No | 376 | 53.3 | Baseline CD4 | <500 | 103 | 14.6 | ≥500 | 28 | 4.0 | Not documented | 574 | 81.4 |
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