In Vitro Antibacterial and Phytochemical Screening of Hypericum perforatum Extract as Potential Antimicrobial Agents against Multi-Drug-Resistant (MDR) Strains of Clinical Origin

Table 2

Susceptibility of MDR isolates to different Hypericum perforatum extracts and MIC values for Hypericum perforatum extracts against MDR strains tested at 10 mg/ml using agar well diffusion assay.

Microorganisms	Extracts
	Methanol extract	n-Hexane	Ethyl acetate	Chloroform	Aqueous	MIC of methanol extract (μg/ml)
	Mean of inhibition zones (mm)
MRSA		NIZ				15.63
E. faecalis		NIZ				3.9
E. coli				NIZ		62.5
K. pneumoniae		NIZ				3.9
P. aeruginosa		NIZ			NIZ	31.25
A. baumannii	NIZ	NIZ	NIZ	NIZ	NIZ	—
P. mirabilis				NIZ		125
S. maltophilia		NIZ				62.5

NIZ: no inhibition zones; MIC = minimum inhibitory concentration; (–) = no activity of the extracts tested.