High Expression of SMO and GLI1 Genes with Poor Prognosis in Malignant Mesothelioma

Table 8

Relationship between expression of SMO and GLI1protein and clinicopathological.

Clinical features		SMO				GLI1
		Negative	Positive			Negative	Positive
Gender		24	106			31	99
Male	60	8	52	1.947	0.163	12	48	0.908	0.341
Female	70	16	54			19	51
Age (years)
<60	39	3	36	4.292	0.038	4	35	5.666	0.017
≥60	91	21	70			27	64
Asbestos exposure history
Yes	85	4	81	30.866	≤0.001	12	73	12.798	≤0.001
No	45	20	25			19	26
Pathological changes
Pleural	60	3	57	13.414	≤0.001	8	52	6.781	0.009
Peritoneal	70	21	49			23	47
Ki67
Negative	36	18	18	32.898	≤0.001	23	13	43.960	≤0.001
Positive	94	6	88			8	86
P53
Negative	51	18	33	15.796	≤0.001	19	32	8.309	0.004
Positive	79	6	73			12	67