High Expression of SMO and GLI1 Genes with Poor Prognosis in Malignant Mesothelioma

Table 10

Clinicopathological multivariate analysis of survival in patients with malignant mesothelioma.

Clinical features	95% CI (SMO)	(SMO)	95% CI (GLI1)	(GLI1)
Gender
Male	0.407 (0.164-1.008)	0.052	0.316 (0.127-0.786)	0.013
Female
Age (years)
<60	1.196 (0.478-2.990)	0.038	1.040 (0.412-2.623)	0.934
≥60
Asbestos exposure history
Yes	5.855 (1.225-27.989)	0.027	6.990 (1.656-29.512)	0.008
No
Pathological changes
Pleural	3.049 (1.062-8.757)	0.038	2.471 (0.939-6.503)	0.067
Peritoneal
P53
Negative	1.103 (0.323-3.769)	0.876	0.904 (0.286-2.862)	0.864
Positive
SMO
Negative	13.240 (3.294-53.219)	≤0.001	/	/
Positive
GLI1
Negative	/	/	10.090 (2.969-34.294)	≤0.001
Positive