Second-Line Antiretroviral Treatment Outcome in HIV-Infected Patients Coinfected with Tuberculosis in Pakistan

Table 1

Characteristics of HIV patients on 2^nd-line ART.

S. No.	Characteristic/risk factor	Total patient No. (%)	HIV^PosTB^Pos patient No. (%) 33 (44.6%)	HIV^PosTB^Neg patient No. (%) 41 (55.4%)	value
1	Gender
	Female	19 (25.7%)	6 (31.6%)	13 (68.4%)	—
	Male	55 (74.3%)	27 (49.1%)	28 (50.9%)	0.186
2	Relationship status
	Married	50 (67.6%)	26 (52.0%)	24 (48.0%)	—
	Single	24 (32.4%)	7 (29.2%)	17 (70.8%)	0.064
3	Employed
	No	37 (50%)	17 (45.9%)	20 (54.1%)	—
	Yes	37 (50%)	16 (43.2%)	21 (56.8%)	0.815
4	Education level
	Illiterate	29 (39.2%)	12 (41.4%)	17 (58.6%)	—
	<10 years of education	36 (48.6%)	17 (47.2%)	19 (52.8%)	0.906
	≥10 years of education	9 (12.2%)	4 (44.4%)	5 (55.6%)	0.895
5	Weight at 2^nd-line ART start (kg)
		—			0.557
6	1^st-line regimen NNRTI initiated
	Efavirenz based	51 (68.9%)	23 (45.1%)	28 (54.9%)	—
	Nevirapine based	23 (31.1%)	10 (43.5%)	13 (56.5%)	0.897
7	Age at start of 2^nd-line ART (year)
		—			0.021
8	Clinical WHO stage at 2^nd-line ART start
	Stages 1 & 2	55 (74.3%)	22 (40.0%)	33 (60.0%)	—
	Stages 3 & 4	19 (25.7%)	11 (57.9%)	8 (42.1%)	0.176
9	Coinfection with hepatitis B & C
		10 (13.5%)	7 (70.0%)	3 (30.0%)	0.082
10	CD4 count at 2^nd-line ART start (cells/mm^3)
		—			0.216
11	VL at 2^nd-line ART start (log10 copies/ml)
		—			0.928

NNRTI: nonnucleoside reverse transcriptase inhibitors.